Event & Seminars

Oct
24
Tue
Réunion Chercheurs @ Salle de réunion U1034
Oct 24 @ 11 h 30 min – 13 h 30 min
Nov
7
Tue
Séminaire Yacine BOULAFTALI @ Salle de bibliothèque U1034
Nov 7 @ 12 h 00 min – 13 h 30 min

Platelets and vascular inflammation

 

Nov
14
Tue
Séminaire Isabelle SAGOT @ Salle Bibliothèque U1034
Nov 14 @ 12 h 00 min – 13 h 00 min

Remodeling of cellular machineries in quiescence.
D. Laporte, L. Gouleme, J. Dompierre, I. Sagot
IBGC – CNRS UMR 5095. 1, rue Camille Saint Saëns. 33077 BORDEAUX cedex.

Isabelle.sagot@ibgc.cnrs.fr

Each cell individually integrates a combination of external and internal signals before committing to another round of cell division. If these signals are not favorable to proliferation, cells exit the division cycle and may enter quiescence, a reversible non-dividing cellular state. Quiescence establishment and exit are therefore key steps involved in major human pathologies like cancers, but also in fundamental biological processes such as development, aging and evolution. Despite its crucial impacts on human health, quiescence remains poorly understood.

Using S. cerevisiae and S. pombe, two evolutionary distant unicellular eukaryotes, as model organisms, we have pioneered the characterization of quiescent cells at the individual cell level. Within the last years, we have demonstrated that upon quiescence establishment, yeast cells remodel various cellular machineries and assemble original cellular structures. Indeed, the actin cytoskeleton is drastically reshaped and forms Actin Bodies, structures composed of stable F-actin filaments. The proteasome is re-localized from the nucleus into cytoplasmic particles that we have called Proteasome Storage Granules. The microtubule cytoskeleton is completely remodeled, and form a unique bundle of very stable microtubules associated with the spindle pole body, the yeast equivalent of the centrosome. Finally, the mitochondrial network is entirely redesigned and its organization can be used to predict individual cell fate upon aging.

Nov
21
Tue
Séminaire Alexandre GUY @ Salle Bibliothèque U1034
Nov 21 @ 12 h 00 min – 13 h 30 min

Résultats de thèse d’Alexandre GUY

Nov
28
Tue
Séminaire Florian GUENIOT @ Salle Bibliothèque U1034
Nov 28 @ 11 h 30 min – 13 h 30 min

Résultats de thèse de Florian GUENIOT

Nov
29
Wed
VIVA Bordeaux Winter School @ Université de Bordeaux - Pey Berland - Amphithéâtre ELLUL
Nov 29 @ 13 h 00 min – Dec 1 @ 14 h 00 min

Site inscription ICI

Dec
5
Tue
Réunion Chercheurs @ Salle de réunion U1034
Dec 5 @ 11 h 30 min – 13 h 00 min
Dec
11
Mon
Thèse Mathieu PERNOT @ Salle Bibliothèque U1034
Dec 11 @ 14 h 00 min – 17 h 00 min

Heure à confirmer

Dec
12
Tue
Séminaire 2 projets de thèse @ Salle Bibliothèque U1034
Dec 12 @ 12 h 00 min – 14 h 00 min
Dec
19
Tue
Séminaire Laetitia ANDRIQUE @ Salle bibliothèque U1034
Dec 19 @ 12 h 00 min – 13 h 30 min

3D production of artificial blood vessels using a microfluidic device

Dr Laetitia ANDRIQUE, phD
LP2N Institut d’Optique/INSERM U1029 LAMC
33405 Talence cedex
laetitiaandrique@hotmail.com
Tel : 06 63 21 33 50
Secrétariat : 05 40 00 87 03
Fax : 05 40 00 87 05