Publications

Selected 2016-2023 basic research publications

2024

Mora P, Laisné M, Bourguignon C, Rouault P, Jaspard-Vinassa B, Maître M, et al. Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis. J Neuroinflammation. 10 oct 2024
INTERVIEW. « La thrombose veineuse est mal connue, souvent bénigne, elle peut être mortelle »
Nicolas N, de Tilly A, Roux E. Blood shear stress during the cardiac cycle and endothelial cell orientation and polarity in the carotid artery of male and female mice. Front Physiol. 12 juill 2024
Debette S, Caro I, Western D, Namba S, Sun N, Kawaguchi S, et al. Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease. Res Sq. 2 juill 2024
Beurton A, Michot M, Hérion FX, Rienzo M, Oddos C, Couffinhal T, et al. Systemic Hemodynamics, Cardiac Mechanics, and Signaling Pathways Induced by Extracorporeal Membrane Oxygenation in a Cardiogenic Shock Model. ASAIO Journal. mars 2024
Hasantari I, Nicolas N, Alzieu P, Leval L, Shalabi A, Grolleau S, et al. Factor H’s Control of Complement Activation Emerges as a Significant and Promising Therapeutic Target for Alzheimer’s Disease Treatment. IJMS. 14 févr 2024
Rouault P, Guimbal S, Cornuault L, Bourguignon C, Foussard N, Alzieu P, et al. Thrombosis in the Coronary Microvasculature Impairs Cardiac Relaxation and Induces Diastolic Dysfunction. ATVB [Internet]. janv 2024

2023

Soukarieh O, Tillet E, Proust C, Dupont C, Jaspard-Vinassa B, Soubrier F, et al. uAUG creating variants in the 5’UTR of ENG causing Hereditary Hemorrhagic Telangiectasia. npj Genom Med. 17 oct 2023
Nicolas N, Dinet V, Roux E. 3D imaging and morphometric descriptors of vascular networks on optically cleared organs. iScience. oct 2023
Guy A, Garcia G, Gourdou-Latyszenok V, Wolff-Trombini L, Josserand L, Kimmerlin Q, et al. Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in JAK2V617F myeloproliferative neoplasms. J Thromb Haemost. 9 sept 2023
Nivoit P, Mathivet T, Wu J, Salemkour Y, Sankar DS, Baudrie V, et al. Correction: Autophagy protein 5 controls flow-dependent endothelial functions. Cell Mol Life Sci. 4 sept 2023
Nivoit P, Mathivet T, Wu J, Salemkour Y, Sankar DS, Baudrie V, et al. Autophagy protein 5 controls flow-dependent endothelial functions. Cell Mol Life Sci. 18 juill 2023
Bougaran P, Bats ML, Delobel V, Rubin S, Vaurs J, Couffinhal T, et al. ROR2/PCP a New Pathway Controlling Endothelial Cell Polarity Under Flow Conditions. ATVB. juill 2023
Wang X, Ramos R, Phan AQ, Yamaga K, Flesher JL, Jiang S, et al. Signalling by senescent melanocytes hyperactivates hair growth. Nature. juin 2023
Munsch G, Proust C, Labrouche-Colomer S, Aïssi D, Boland A, Morange PE, et al. Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels. NAR Genom Bioinform. juin 2023
Duplaa, C. Un facteur causal de l’insuffisance cardiaque – L’accumulation de liquide dans l’espace extracellulaire du myocarde. Med Sci (Paris). 21 mars 2023
Koukouritaki SB, Thinn AMM, Ashworth K, Fang J, Slater HS, Du LM, et al. A Single F153Sβ3 Mutation Causes Constitutive Integrin αIIbβ3 Activation in a Variant Form of Glanzmann Thrombasthenia. Blood Adv. 8 mars 2023

2022

Cornuault L, Rouault P, Duplàa C, Couffinhal T, Renault MA. Endothelial Dysfunction in Heart Failure With Preserved Ejection Fraction: What are the Experimental Proofs? Front Physiol. 8 juill 2022
Dinet V, Arouche-Delaperche L, Dégardin J, Naud MC, Picaud S, Krantic S. Concomitant Retinal Alterations in Neuronal Activity and TNFα Pathway Are Detectable during the Pre-Symptomatic Stage in a Mouse Model of Alzheimer’s Disease. Cells. 16 mai 2022
Abelanet A, Camoin M, Rubin S, Bougaran P, Delobel V, Pernot M, et al. Increased Capillary Permeability in Heart Induces Diastolic Dysfunction Independently of Inflammation, Fibrosis, or Cardiomyocyte Dysfunction. Arterioscler Thromb Vasc Biol. 5 mai 2022
Mishra A, Duplaà C, Vojinovic D, Suzuki H, Sargurupremraj M, Zilhão NR, et al. Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain. 2 mai 2022;awab432.
Rubin S, Bougaran P, Martin S, Abelanet A, Delobel V, Pernot M, et al. PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice. Arterioscler Thromb Vasc Biol. mai 2022;42(5):597‑609.
Gueniot F, Rubin S, Bougaran P, Abelanet A, Morel JL, Bontempi B, et al. Targeting Pdzrn3 maintains adult blood-brain barrier and central nervous system homeostasis. J Cereb Blood Flow Metab. avr 2022;42(4):613‑29.
Abdulrahman N, Ibrahim M, Joseph JM, Elkoubatry HM, Al-Shamasi A-A, Rayan M, et al. Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression. Mol Cell Biochem. 25 mars 2022;
Moustafa DA, Imran Z, Ismail R, Rayan M, Gadeau A-P, Eldassouki H, et al. Evaluating the effects of sodium glucose co-transporter -2 inhibitors from a renin-angiotensin-aldosterone system perspective in patients infected with COVID-19: contextualizing findings from the dapagliflozin in respiratory failure in patients with COVID-19 study. Mol Biol Rep. mars 2022;49(3):2321‑4.
Amatruda M, Chapouly C, Woo V, Safavi F, Zhang J, Dai D, et al. Astrocytic junctional adhesion molecule-A regulates T-cell entry past the glia limitans to promote central nervous system autoimmune attack. Brain Commun. 18 févr 2022;4(2):fcac044.
Bats M-L, Peghaire C, Delobel V, Dufourcq P, Couffinhal T, Duplàa C. Wnt/frizzled Signaling in Endothelium: A Major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity. Cold Spring Harb Perspect Med. 24 janv 2022;a041219.
Pernot M, Jaspard-Vinassa B, Abelanet A, Rubin S, Forfar I, Jeanningros S, et al. Decrease of Pdzrn3 is required for heart maturation and protects against heart failure. Sci Rep. 7 janv 2022;12(1):8.

2021

Nicolas N, Nicolas N, Roux E. Computational Identification and 3D Morphological Characterization of Renal Glomeruli in Optically Cleared Murine Kidneys. Sensors (Basel). 9 nov 2021
Al-Shamasi A-A, Elkaffash R, Mohamed M, Rayan M, Al-Khater D, Gadeau A-P, et al. Crosstalk between Sodium-Glucose Cotransporter Inhibitors and Sodium-Hydrogen Exchanger 1 and 3 in Cardiometabolic Diseases. Int J Mol Sci. 24 nov 2021;22(23):12677.
Gueniot F, Rubin S, Bougaran P, Abelanet A, Morel JL, Bontempi B, et al. Targeting Pdzrn3 maintains adult blood-brain barrier and central nervous system homeostasis. J Cereb Blood Flow Metab. 13 oct 2021;271678X211048981.
Hollier P-L, Chapouly C, Diop A, Guimbal S, Cornuault L, Gadeau A-P, et al. Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability. Cardiovasc Res. 1 nov 2021;117(12):2489‑501.
Dumas P-Y, Villacreces A, Guitart AV, El-Habhab A, Massara L, Mansier O, et al. Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia. Clin Cancer Res. août 2021;
Delaunay K, Sellam A, Dinet V, Moulin A, Zhao M, Gelizé E, et al. Meteorin Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration. J Clin Med. 2 juill 2021;10(13):2973.
Nicolas N, Roux E. 3D Imaging and Quantitative Characterization of Mouse Capillary Coronary Network Architecture. Biology. 2021 Apr 7.
Guimbal S, Cornuault L, Rouault L, Hollier P.L, Chapouly C, Bats M.L, Imbault J, Gadeau A.P, Couffinhal T, Renault M.A. Mast Cells Are the Trigger of Small Vessel Disease and Diastolic Dysfunction in Diabetic Obese Mice.2021 Apr. Arteriosclerosis, Thrombosis, and Vascular Biology. doi : 10.1161/ATVBAHA.121.315900.
Luque Paz D, Riou J, Verger E, Cassinat B, Chauveau A, Ianotto J-C, et al. Genomic analysis of primary and secondary myelofibrosis redefines the prognostic impact of ASXL1 mutations: a FIM study. Blood Adv. 9 mars 2021;5(5):1442‑51.
Fawaz S, Mansier O, Pucheu Y, Marti S, Leroy H, Gaufroy A, Broitman J, James C, Couffinhal T. Clonal haematopoiesis and cardiovascular diseases. Arch Cardiovasc Dis. 2021 Mar 10.
Guy A, Poisson J, James C. Pathogenesis of cardiovascular events in BCR-ABL1-negative myeloproliferative neoplasms. Leukemia 2021 Mar 03
Rubin S, Boulestreau R, Gosse P, Combe C. A plea for renin–angiotensin system blockers as first-line treatment in cases of severe acute hypertension. Nephrology Dialysis Transplantation [En ligne]. avril 2021 [cité le 9 janv 2021];gfaa313. Disponible: https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfaa313/6048412
Bertrand C, Saulnier P-J, Potier L, Croyal M, Blanchard V, Gand E, et al. Plasma concentrations of lipoproteins and risk of lower-limb peripheral artery disease in people with type 2 diabetes: the SURDIAGENE study. Diabetologia. 6 janv 2021;
Rigalleau V, Foussard N, Bertrand A, Monlun M, Blanco L, Mohammedi K. Lung cancer and diabetes: A role for advanced glycation end-products? Eur J Clin Invest. janv 2021;51(1):e13389.

2020

Rienzo M, Imbault J, El Boustani Y, Beurton A, Carlos Sampedrano C, Pasdois P, Pernot M, Bernus O, Haïssaguerre M, Couffinhal T, Ouattara A. A total closed chest sheep model of cardiogenic shock by percutaneous intracoronary ethanol injection. Sci Rep 2020;10:12417.
Bats M, Bougaran P, Peghaire C, Gueniot F, Abelanet A, Chan H, Séguy C, Jeanningros S, Jaspard‐Vinassa B, Couffinhal T, Duplàa C, Dufourcq P. Therapies targeting Frizzled‐7/β‐catenin pathway prevent the development of pathological angiogenesis in an ischemic retinopathy model. FASEB j 2020;34:1288–1303.
Silva H, Roux É, Gadeau A-P, Rodrigues LM. Wavelet Analysis of Microcirculatory Flowmotion Reveals Cardiovascular Regulatory Mechanisms–Data from a Beta-Blocker. Applied Sciences 2020;10:4000.
Roux E. Are biological functions selected effects?: Justin Garson: What biological functions are and why they matter. Metascience 2020;29:107–111.
Riaz S, Abdulrahman N, Uddin S, Jabeen A, Gadeau AP, Fliegel L, Mraiche F. Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B. Eur J Pharmacol 2020;173420.
Poisson J, Tanguy M, Davy H, Camara F, El Mdawar M-B, Kheloufi M, Dagher T, Devue C, Lasselin J, Plessier A, Merchant S, Blanc-Brude O, Souyri M, Mougenot N, Dingli F, Loew D, Hatem SN, James C, Villeval J-L, Boulanger CM, Rautou P-E. Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm. J Clin Invest 2020;130:2630–2643.
Guy A, Danaee A, Paschalaki K, Boureau L, Rivière E, Etienne G, Mansier O, Laffan M, Sekhar M, James C. Absence of JAK2V617F Mutated Endothelial Colony-Forming Cells in Patients With JAK2V617F Myeloproliferative Neoplasms and Splanchnic Vein Thrombosis. Hemasphere 2020;4:e364.
Fulmer D, Toomer KA, Glover J, Guo L, Moore K, Moore R, Stairley R, Gensemer C, Abrol S, Rumph MK, Emetu F, Lipschutz J, McDowell C, Bian J, Wang C, Beck T, Wessels A, Renault M-A, Norris R. Desert Hedgehog-Primary Cilia Cross Talk Shapes Mitral Valve Tissue by Organizing Smooth Muscle Actin. Dev Biol 2020;
Cottin L, Riou J, Orvain C, Ianotto JC, Boyer F, Renard M, Truchan-Graczyk M, Murati A, Jouanneau-Courville R, Allangba O, Mansier O, Burroni B, Rousselet M-C, Quintin-Roué I, Martin A, Sadot-Lebouvier S, Delneste Y, Chrétien J-M, Hunault-Berger M, Blanchet O, Lippert E, Ugo V, Luque Paz D. Sequential mutational evaluation of CALR -mutated myeloproliferative neoplasms with thrombocytosis reveals an association between CALR allele burden evolution and disease progression. Br J Haematol 2020;188:935–944.
Borras C, Delaunay K, Slaoui Y, Abache T, Jorieux S, Naud M-C, Sanharawi ME, Gelize E, Lassiaz P, An N, Kowalczuk L, Ayassami C, Moulin A, Behar-Cohen F, Mascarelli F, Dinet V. Mechanisms of FH Protection Against Neovascular AMD. Front Immunol 2020;11:443.

2019

Mansier O, Kilani B, Guitart AV, Guy A, Gourdou-Latyszenok V, Marty C, Parrens M, Plo I, Vainchenker W, James C. Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells. Blood 2019;134:2383–2387.
Kilani B, Gourdou-Latyszenok V, Guy A, Bats M-L, Peghaire C, Parrens M, Renault M-A, Duplàa C, Villeval J-L, Rautou P-E, Couffinhal T, James C. Comparison of endothelial promoter efficiency and specificity in mice reveals a subset of Pdgfb-positive hematopoietic cells. J Thromb Haemost 2019;17:827–840.
Guy A, Gourdou-Latyszenok V, Le Lay N, Peghaire C, Kilani B, Dias JV, Duplaa C, Renault M-A, Denis C, Villeval JL, Boulaftali Y, Jandrot-Perrus M, Couffinhal T, James C. Vascular endothelial cell expression of JAK2V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression. Haematologica 2019;104:70–81.
Guy A, Favre S, Labrouche-Colomer S, Deloison L, Gourdou-Latyszenok V, Renault MA, Riviere E, James C. High circulating levels of MPO-DNA are associated with thrombosis in patients with MPN. Leukemia 2019;33:2544–2548.
Chapouly C, Guimbal S, Hollier P-L, Renault M-A. Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance. IJMS 2019;20:3076.
Pillois X, Guy A, Choquet É, James C, Tuffigo M, Viallard J-F, Garcia C, Bordet J-C, Jandrot-Perrus M, Payrastre B, Fiore M. First description of an IgM monoclonal antibody causing αIIb β3 integrin activation and acquired Glanzmann thrombasthenia associated with macrothrombocytopenia. J Thromb Haemost 2019;17:795–802.
Monteiro Rodrigues L, Nazaré Silva H, Ferreira H, Gadeau A-P. Characterizing Vascular Dysfunction in Genetically Modified Mice through the Hyperoxia Model. IJMS 2019;20:2178.
Bermúdez-Moretti M, Gulías JF, Valencia-Guillén J, Muñoz SA, Forfar I, Correa-García S. Monitoring changes in the cellular content of biomolecules during ageing with FTIR spectroscopy. Vibrational Spectroscopy 2019;105:102972.
Abdelaziz Mohamed I, Gadeau A-P, Hasan A, Abdulrahman N, Mraiche F. Osteopontin: A Promising Therapeutic Target in Cardiac Fibrosis. Cells 2019;8:1558.
Borras C, Canonica J, Jorieux S, Abache T, El Sanharawi M, Klein C, Delaunay K, Jonet L, Salvodelli M, Naud M-C, Arsenijevic Y, Shalabi A, Souchaud L, Behar-Cohen F, Dinet V. CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex. Sci Rep 2019;9:13873.
Dinet V, Petry KG, Badaut J. Brain–Immune Interactions and Neuroinflammation After Traumatic Brain Injury. Front Neurosci 2019;13:1178

2018

Mansier O, Luque Paz D, Ianotto J-C, Le Bris Y, Chauveau A, Boyer F, Conejero C, Fitoussi O, Riou J, Adiko D, Touati M, Chauzeix J, Viallard J-F, Béné MC, Giraudier S, Ugo V, Lippert E. Clinical and biological characterization of MPN patients harboring two driver mutations, a French intergroup of myeloproliferative neoplasms (FIM) study. Am J Hematol 2018;93:E84–E86.
Caradu C, Guy A, James C, Reynaud A, Gadeau A-P, Renault M-A. Endogenous Sonic Hedgehog limits inflammation and angiogenesis in the ischaemic skeletal muscle of mice. Cardiovasc Res 2018;114:759–770.
Caradu C, Couffinhal T, Chapouly C, Guimbal S, Hollier P-L, Ducasse E, Bura-Rivière A, Dubois M, Gadeau A-P, Renault M-A. Restoring Endothelial Function by Targeting Desert Hedgehog Downstream of Klf2 Improves Critical Limb Ischemia in Adults. Circ Res 2018;123:1053–1065.
Pillois X, Peters P, Segers K, Nurden AT. In silico analysis of structural modifications in and around the integrin αIIb genu caused by ITGA2B variants in human platelets with emphasis on Glanzmann thrombasthenia. Molecular Genetics & Genomic Medicine 2018;6:249–260.
Nurden AT, Pillois X. ITGA2B and ITGB3 gene mutations associated with Glanzmann thrombasthenia. Platelets 2018;29(1).
Monteiro Rodrigues L, Silva H, Ferreira H, Renault M-A, Gadeau A-P. Observations on the perfusion recovery of regenerative angiogenesis in an ischemic limb model under hyperoxia. Physiol Rep 2018;6:e13736.
Fiore M, Oiron R d’, Pillois X, Alessi M-C. Anti-αIIb β3 immunization in Glanzmann thrombasthenia: review of literature and treatment recommendations. Br J Haematol 2018;181:173–182.
Favier M, Bordet JC, Favier R, Gkalea A, Pillois X, Rameau P, Debili N, Alessi MC, Nurden P, Raslova H, Nurden A. Mutations of the integrin αIIb/β3 intracytoplasmic salt bridge cause macrothrombocytopenia and enlarged platelet α-granules. Am J Hematol 2018;93:195–204.
Dumas P-Y, Mansier O, Prouzet-Mauleon V, Koya J, Villacreces A, Brunet de la Grange P, Luque Paz D, Bidet A, Pasquet J-M, Praloran V, Salin F, Kurokawa M, Mahon F-X, Cardinaud B, Lippert E. MiR-10a and HOXB4 are overexpressed in atypical myeloproliferative neoplasms. BMC Cancer 2018;18:1098.
Abdulrahman N, Jaspard-Vinassa B, Fliegel L, Jabeen A, Riaz S, Gadeau A-P, Mraiche F. Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase. Physiol Genomics 2018;50:332–342.

2017

Sewduth RN, Kovacic H, Jaspard-Vinassa B, Jecko V, Wavasseur T, Fritsch N, Pernot M, Jeanningros S, Roux E, Dufourcq P, Couffinhal T, Duplaa C. PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability. Sci signal 2017;10:eaag3209.
Markovic R, Peltan J, Gosak M, Horvat D, Zalik B, Seguy B, Chauvel R, Malandain G, Couffinhal T, Duplaa C, Marhl M, Roux E. Planar cell polarity genes frizzled4 and frizzled6 exert patterning influence on arterial vessel morphogenesis. PLoS One 2017;12:e0171033.
Roux E, Marhl M. Theoretical Analysis of the Vascular System and its Relation to Adrian Bejan’s constructal Theory. Journal of Theoretical and Applied Vascular Research JTAVR 2017;13.
Peuchant E, Bats M, Moranvillier I, Lepoivre M, Guitton J, Wendum D, Lacombe M, Moreau‐Gaudry F, Boissan M, Dabernat S. Metastasis suppressor NM23 limits oxidative stress in mammals by preventing activation of stress‐activated protein kinases/JNKs through its nucleoside diphosphate kinase activity. FASEB j 2017;31:1531–1546.
Nurden P, Bordet JC, Pillois X, Nurden AT. An intracytoplasmic B3 Leu718 deletion in a patient with a novel platelet phenotype. Blood Adv 2017;1:494–499.
Labbé P, Faure E, Lecointe S, Le Scouarnec S, Kyndt F, Marrec M, Le Tourneau T, Offman B, Duplaa C, Zaffran S, Schott JJ, Merot J. The alternatively spliced LRRFIP1 Isoform-1 is a key regulator of the Wnt/β-catenin transcription pathway. Biochimica et biophysica acta 2017;1864:1142–1152.
Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw AT, Hara Y, Mariani JN, Sawai S, Flodby P, Crandall ED, Borok Z, Sofroniew MV, Chapouly C, John GR. Astrocytic tight junctions control inflammatory CNS lesion pathogenesis. J Clin Invest 2017;127:3136–3151.
Fiore M, Goulas C, Pillois X. A new mutation in TUBB1 associated with thrombocytopenia confirms that C-terminal part of β1-tubulin plays a role in microtubule assembly. Clin Genet 2017;91:924–926.
Chenu C, Adlanmerini M, Boudou F, Chantalat E, Guihot A-L, Toutain C, Raymond-Letron I, Vicendo P, Gadeau A-P, Henrion D, Arnal J-F, Lenfant F. Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions. Arterioscler Thromb Vasc Biol 2017;37:909–919.

2016

Peghaire C, Bats ML, Sewduth RN, Jeanningros S, Jaspard B, Couffinhal T, Duplaa C, Dufourcq P. Fzd7 (Frizzled-7) Expressed by Endothelial Cells Controls Blood Vessel Formation Through Wnt/β-Catenin Canonical Signaling. Arterioscler Thromb Vasc Biol 2016;36:2369–2380.
Merched A, Daret D, Li L, Franzl N, Sauvage-Merched M. Specific autoantigens in experimental autoimmunity-associated atherosclerosis. Faseb J 2016;
Guillabert-Gourgues A, Jaspard B, Bats ML, Sewduth RN, Franzl N, Peghaire C, Jeanningros S, Moreau C, Roux E, Larrieu Laharque F, Dufourcq P, Couffinhal T, Duplaa C. Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway. Mol Biol Cell 2016;27:941–953.
Chapouly C, Yao Q, Vandierdonck S, Larrieu Laharque F, Mariani JN, Gadeau AP, Renault MA. Impaired Hedgehog signalling-induced endothelial dysfunction is sufficient to induce neuropathy: implication in diabetes. Cardiovasc Res 2016;217-227.
Reant P, Metras A, Detaille D, Reynaud A, Diolez P, Jaspard B, Roudaut R, Ouattara A, Barandon L, Dos Santos P, Lafitte S. Impact of Afterload Increase on Left Ventricular Myocardial Deformation Indices. J Am Soc Echocardiogr 2016;1217–1228.
Pillois X, Nurden A. Linkage disequilibrium amongst ITGA2B and ITGB3 gene variants in patients with Glanzmann thrombasthenia confirms that most disease-causing mutations are recent. Br J Haematol 2016;686–695.
Mansier O, Migeon M, Saint-Lézer A, James C, Verger E, Robin M, Socié G, Bidet A, Mahon F-X, Cassinat B, Lippert E. Quantification of the Mutant CALR Allelic Burden by Digital PCR. The Journal of Molecular Diagnostics 2016;18:68–74.
Barron E, Passagne I, Auger A, Travo A, Rascol E, L’Azou B, Forfar I. Monitoring biological effects of 20 nm versus 100 nm silica nanoparticles induced on a human renal cell line using Fourier transform infrared spectroscopy. Anal Methods 2016;8:2233–2242.

Selected 2016-2023 clinical publications

2024

Boulestreau R, Lorthioir A, Dreau H, Persu A, Cremer A, Tharaux PL, et al. Baseline characteristics of the first 302 patients included for acute malignant hypertension crisis in the prospective multidisciplinary HAMA cohort. J Hypertens. 1 déc 2024
Lahouati M, Brousse X, Dias Meireles V, Rignol L, Bientz L, Xuereb F, et al. Real-life use of temocillin in the treatment of bone and joint infections due to extended spectrum β-lactamase-producing Enterobacterales. JAC Antimicrob Resist. déc 2024
Saultier P, Grino M, Falaise C, Voisin S, Lavenu-Bombled C, Ibrahim-Kosta M, et al. Efficacy and safety of recombinant activated factor VII in Glanzmann thrombasthenia: A systematic literature review. Haemophilia. 27 nov 2024
Guy A, Morange PE, James C. How I approach the treatment of thrombotic complications in patients with myeloproliferative neoplasms. Blood. 14 nov 2024
de Courson H, Cane G, d’Auzac A, Barbieri A, Derot S, Carrie C, et al. Augmented Renal Clearance: Prevalence, Risk Factors and Underlying Mechanism in Critically Ill Patients with Subarachnoid Hemorrhage. Neurocrit Care. 7 nov 2024
Mathieu L, Brunetti C, Detchepare J, Flambard M, Germain C, Langouet E, et al. Reducing the prime cardiopulmonary bypass volume during paediatric cardiac surgery. Perfusion. 1 nov 2024
Liegey JS, Cremer A, Lucas L, Gosse P, Debeugny S, Rubin S, et al. Course of brain damage following malignant hypertension. J Hum Hypertens. 1 nov 2024
Le Grand Q, Tsuchida A, Koch A, Imtiaz MA, Aziz NA, Vigneron C, et al. Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel disease. Mol Psychiatry [Internet]. Novembre 2024 [cité 28 juin 2024]
Huynh C, Crubezy I, Trin K, Perino J, Ong N, Ramaroson H, et al. Cost analysis study comparing the impact of treatment with aprotinin versus tranexamic acid in cardiac surgery under cardiopulmonary bypass. Ann Pharm Fr. nov 2024
Lavoillotte J, Mohammedi K, Salenave S, Furnica RM, Maiter D, Chanson P, et al. Personalized Noninvasive Diagnostic Algorithms Based on Urinary Free Cortisol in ACTH-dependant Cushing’s Syndrome. J Clin Endocrinol Metab. 15 oct 2024
Durand P, Pottier V, Debordeaux F, Mesguich C, Duffau P, Lazaro E, et al. Course of immune thrombocytopenia according to the site of platelet destruction identified by indium-111 platelet scintigraphy. Br J Haematol. 15 oct 2024
Lahouati M, Tinévez C, Gabriel F, Xuereb F, Lefranc M, Dauchy FA. Efficacy of rezafungin in a case of Candida spondylodiskitis. J Bone Jt Infect. 7 oct 2024
Prével R, Boyer A, Gruson D, Orieux A. Catheter ablation for atrial fibrillation, atrio-oesophageal fistula, cerebral air embolism, and hyperbaric oxygen therapy. Lancet. 14 sept 2024
Mohammedi K, Pigeyre M, Bosch J, Yusuf S, Gerstein HC. Relationships between ankle blood pressure indices and major adverse cardiovascular events in people with and without type 2 diabetes. Cardiovasc Diabetol. 3 sept 2024
Dubut J, Goin V, Derray C, Huguenin Y, Fiore M. Targeting Tissue Factor Pathway Inhibitor with concizumab to improve haemostasis in patients with Glanzmann thrombasthenia: an in vitro study. Journal of Thrombosis and Haemostasis. sept 2024
Cane G, De Courson H, Robert C, Fukutomi H, Marnat G, Tourdias T, et al. Cerebral Hemodynamics and Levosimendan Use in Patients with Cerebral Vasospasm and Subarachnoid Hemorrhage: An Observational Perfusion CT-Based Imaging Study. Neurocrit Care [Internet]. août 2024 [cité 21 mars 2024]
Mohammedi K, Hess S, McQueen M, Pigeyre M, Lee SF, Pare G, et al. Determinants of serious health outcome‐free status in middle‐aged and older people with dysglycaemia: Exploratory analysis of the ORIGIN trial. Diabetes Obesity Metabolism. août 2024
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Orieux A, Birot R, Gruson D, Prevel R. Horner’s syndrome after chest drain insertion due to pneumothorax. Med Intensiva (Engl Ed). 15 juin 2024
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Galtier J, Drevon L, Le Bris Y, Giraudier S, Wemeau M, Legros L, et al. Role of red cell mass evaluation in myeloproliferative neoplasms with splanchnic vein thrombosis and normal hemoglobin value: a study of the France Intergroupe des Syndromes myeloprolifératifs. haematol [Internet]. juin 2024 [cité 21 mars 2024]
Martin-Latry Karin – Publication d’un livre disponible en librairie et en ligne : La maladie chronique – Vivre avec au quotidien (editions-ellipses.fr)
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Usart M, Hansen N, Stetka J, Almeida Fonseca T, Guy A, Kimmerlin Q, et al. The glutaminase inhibitor CB-839 targets metabolic dependencies of JAK2-mutant hematopoiesis in MPN. Blood Adv. 14 mai 2024
Mohammedi K, Pigeyre M, Bosch J, Yusuf S, Gerstein HC. Arm and ankle blood pressure indices, and peripheral artery disease, and mortality: a cohort study. European Heart Journal. mai 2024
Brett VE, Dignat George F, James C. Circulating endothelial cells in pathophysiology. Current Opinion in Hematology. mai 2024
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Grouthier V, Bachelot A. Long-term outcomes in non-CAH 46,XX DSD. Front Endocrinol. 30 avr 2024
Lavoillotte J, Mohammedi K, Salenave S, Furnica RM, Maiter D, Chanson P, et al. Personalized Noninvasive Diagnostic Algorithms Based on Urinary Free Cortisol in ACTH-dependant Cushing’s Syndrome. The Journal of Clinical Endocrinology & Metabolism. 13 avr 2024
De Courson H, Loiseau A, Chadefaux G, Biais M. Response to commentary “The importance of assessing left ventricular longitudinal function in presence of increased afterload”. Crit Care. 29 mars 2024
Rivière E, Jourde W, Gensous N, Demant X, Ribeiro E, Duffau P, et al. Efficacy and safety of Infliximab in systemic sarcoidosis according to GenPhenReSa organ-involvement phenotype: a retrospective study of 55 patients. Respir Res. 14 mars 2024
Le Joncour S, Gohier P, Rombaut F, Soulet C, Maachi I, Xuereb F. Le pharmacien clinicien, un maillon indispensable dans la nouvelle gradation de prise en charge des patients ambulatoires. Annales Pharmaceutiques Françaises. mars 2024
Rubin S, Orieux A, Prezelin-Reydit M, Garric A, Picard Y, Mellati N, et al. Impact of dexamethasone in severe COVID-19-induced acute kidney injury: a multicenter cohort study. Ann Intensive Care. 13 févr 2024
Mouthon P, Guy A, d’Oiron R, Harroche A, Lebreton A, Gourguechon C, et al. Acquired haemophilia A in paediatric patients: A retrospective French cohort of eight cases. Br J Haematol. févr 2024
Alkhami F, Borderie G, Foussard N, Larroumet A, Blanco L, Barbet-Massin MA, et al. The skin autofluorescence may help to select patients with Type 2 diabetes candidates for screening to revascularization procedures. Cardiovasc Diabetol. 13 janv 2024
Lee CSM, Huguenin Y, Pillois X, Moulieras M, Marcy E, Whittaker S, et al. In vitro characterization of rare anti-αIIbβ3 isoantibodies produced by patients with Glanzmann thrombasthenia that severely block fibrinogen binding and generate procoagulant platelets via complement activation. Research and Practice in Thrombosis and Haemostasis. janv 2024

2023

Chambord J, Chauveau B, Djabarouti S, Vignaud J, Taton B, Moreau K, et al. Measurement of the Immunosuppressant Possession Ratio by Transplant Clinical Pharmacists Captures a Non-Adherence Associated With Antibody-Mediated Rejection. Transpl Int. 28 nov 2023
Mohammedi K, Cordon A, Rigalleau V, Foussard N, Bairras-Martin C, Couffinhal T, et al. Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records. Cardiovasc Diabetol. 28 nov 2023
De Courson H, Chadefaux G, Loiseau A, Georges D, Biais M. Myocardial dysfunction assessed by speckle-tracking in good-grade subarachnoid hemorrhage patients (WFNS 1–2): a prospective observational study. Crit Care. 21 nov 2023
Mathieu L, Beurton A, Rougier N, Flambard M, Germain C, Pernot M, et al. Heparin consumption and inflammatory response according to the coating of cardiopulmonary bypass circuits in cardiac surgery: A retrospective analysis. Perfusion. 9 nov 2023
Cholley B, Bojan M, Guillon B, Besnier E, Mattei M, Levy B, et al. Correction: Overview of the current use of levosimendan in France: a prospective observational cohort study. Ann Intensive Care. 29 sept 2023
Harris SB, Mohammedi K, Bertolini M, Carlyle M, Walker V, Zhou FL, et al. Patient and physician perspectives and experiences of basal insulin titration in type 2 diabetes in the United States: Cross-sectional surveys. Diabetes Obes Metab. 25 sept 2023
Hérion FX, Beurton A, Oddos C, Nubret K, Aguerreche C, Quessard A, et al. Multidisciplinary cardiogenic shock team approach improves the long-term outcomes of patients suffering from refractory cardiogenic shock treated with short-term mechanical circulatory support. Eur Heart J Acute Cardiovasc Care. 15 sept 2023
Mansour A, Beurton A, Godier A, Rozec B, Zlotnik D, Nedelec F, et al. Combined Platelet and Red Blood Cell Recovery during On-pump Cardiac Surgery Using same^TM by i-SEP Autotransfusion Device: A First-in-human Noncomparative Study (i-TRANSEP Study). Anesthesiology. 1 sept 2023
Liegey JS, Fawaz S, Ducos C, Pucheu Y, Boulestreau R, Sibon I, et al. Predictive utility of stress tests in the detection of asymptomatic coronary artery disease in atherosclerotic stroke patients. J Stroke Cerebrovasc Dis. sept 2023
Cholley B, Bojan M, Guillon B, Besnier E, Mattei M, Levy B, et al. Overview of the current use of levosimendan in France: a prospective observational cohort study. Ann Intensive Care. 8 août 2023
Fiore M, Giraudet JS, Alessi MC, Falaise C, Desprez D, d’Oiron R, et al. Emergency management of patients with Glanzmann thrombasthenia: consensus recommendations from the French reference center for inherited platelet disorders. Orphanet J Rare Dis. 29 juin 2023
Abel A, Lazaro E, Ralazamahaleo M, Pierrisnard E, Suzon B, Bonnet F, et al. Phenotypic Profiles Among 72 Caucasian and Afro-Caribbean Patients with Antisynthetase Syndrome Involving Anti-PL7 or Anti-PL12 Autoantibodies. Eur J Intern Med. 15 juin 2023
Deffieux X, Rousset-Jablonski C, Gantois A, Brillac T, Maruani J, Maitrot-Mantelet L, et al. [Pelvic exam in gynecology and obstetrics: Guidelines for clinical practice]. Gynecol Obstet Fertil Senol. juin 2023
Durand P, Pottier V, Mesguich C, Debordeaux F, Lazaro E, Viallard JF, et al. Utility of indium-111 platelet scintigraphy for understanding the mechanism of thrombocytopenia associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Exp Hematol Oncol. 30 mai 2023
Crickx E, Ebbo M, Rivière E, Souchaud-Debouverie O, Terriou L, Audia S, et al. Combining thrombopoietin receptor agonists with immunosuppressive drugs in adult patients with multirefractory immune thrombocytopenia, an update on the French experience. Br J Haematol. 29 mai 2023
Foussard N, Larroumet A, Ferrière A, Blanco L, Mohammedi K, Rigalleau V. Comment on Tang et al. The Impact of Carbamylation and Anemia on HbA1c’s Association With Renal Outcomes in Patients With Diabetes and Chronic Kidney Disease. Diabetes Care 2023;46:130–137. Diabetes Care. 1 mai 2023
Carrié C, Rieu B, Benard A, Trin K, Petit L, Massri A, et al. Early non-invasive ventilation and high-flow nasal oxygen therapy for preventing endotracheal intubation in hypoxemic blunt chest trauma patients: the OptiTHO randomized trial. Crit Care. 26 avr 2023
Rivière E, Thiébaut R, Lazaro E, Guy A, James C, Mansier O, et al. Assessment of circulating blood lymphocytes in adult patients on rituximab to treat immune thrombocytopenia: Circulating number of NK cells is associated with the response at 6 months. Br J Haematol. 20 avr 2023
Cèbe A, Dessane B, Gohier P, Bernadou JM, Venet A, Xuereb F, et al. Hospital Production of Sterile 2% Propofol Nanoemulsion: Proof of Concept. Pharmaceutics. 10 mars 2023
Foussard N, Dari L, Ducasse E, Rigalleau V, Mohammedi K, Caradu C. Lower-limb peripheral arterial disease and amputations in people with diabetes: Risk factors, prognostic value and management. La Presse Médicale. mars 2023
Brett V, Lechevalier N, Trimoreau F, Dussiau C, Dimicoli‐Salazar S, Coster L, et al. The presence of a chromosomal abnormality in cytopenia without dysplasia identifies a category of high‐risk clonal cytopenia of unknown significance. Genes Chromosomes & Cancer. mars 2023
Acquier M, Zabala A, de Précigout V, Delmas Y, Dubois V, de la Faille R, et al. Performance of real-time PCR in suspected haemodialysis catheter-related bloodstream infection: a proof-of-concept study. Clin Kidney J. mars 2023
Guy A, Helzy K, Mansier O, Bordet JC, Rivière E, Fiore M, et al. Platelet function studies in myeloproliferative neoplasms patients with Calreticulin or JAK2V617F mutation. Research and Practice in Thrombosis and Haemostasis. févr 2023
Borderie G, Foussard N, Larroumet A, Blanco L, Domenge F, Mohammedi K, et al. Albuminuric diabetic kidney disease predicts foot ulcers in type 2 diabetes. Journal of Diabetes and its Complications. févr 2023
Harris SB, Mohammedi K, Bertolini M, White J, Walker V, Zhou FL, et al. Patient perspectives and experiences with basal insulin titration in type 2 diabetes in the United States: A cross‐sectional survey. Diabetes Obesity Metabolism. 31 janv 2023
Huguenin Y, Levoir L, Bouton M, Fiore M. High Rates of Anti-α_IIbβ₃ Antibodies Produced by a Glanzmann Thrombasthenia Patient after First and Unique Red Blood Cells Administration. Acta Haematol. 2023

2022

de Courson H, Proust-Lima C, Tuaz E, Georges D, Verchère E, Biais M. Relationship Between Brain Tissue Oxygen and Near-Infrared Spectroscopy in Patients with Nontraumatic Subarachnoid Hemorrhage. Neurocrit Care. déc 2022
Petria I, Albuquerque S, Varoquaux G, Vie JJ, Venteclef N, Mohammedi K, et al. Body-weight variability and risk of cardiovascular outcomes in patients with type 1 diabetes: a retrospective observational analysis of data from the DCCT/EDIC population. Cardiovasc Diabetol. 17 nov 2022
Vergès B, Aboyans V, Angoulvant D, Boutouyrie P, Cariou B, Hyafil F, et al. Protection against stroke with glucagon-like peptide-1 receptor agonists: a comprehensive review of potential mechanisms. Cardiovasc Diabetol. 15 nov 2022
Roullet S, Rivoire T, Houssin C, Labrouche S, Paquin S, Nouette-Gaulain K, et al. Hemostatic Effects of Tranexamic Acid in Cesarean Delivery: An Ancillary Study of the TRAAP2 Study. Thromb Haemost. nov 2022
Sanchez M, Kannengiesser C, Hoang S, Potier L, Fumeron F, Venteclef N, et al. Leukocyte telomere length, allelic variations in related genes and risk of coronary heart disease in people with long-standing type 1 diabetes. Cardiovasc Diabetol. 11 oct 2022
Rami Arab L, Dabernat S, Boutin J, Bordenave C, Karmani M, Colombiès B, et al. Impact of Albumin Assays in the Diagnosis of Malnutrition in Hemodialysis Patients: A Cohort Study. Journal of Renal Nutrition. oct 2022
Rivière E, Bazin C. Superior Vena Cava Thrombosis. The American Journal of Medicine. sept 2022
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Fourgeaud M, Lebreton L, Belabbas K, Di Filippo M, Rigalleau V, Couffinhal T, et al. Phenotypic and genotypic characterization of familial hypercholesterolemia in French adult and pediatric populations. J Clin Lipidol. juin 2022
Perino J, Corand V, Laurent E, Théophile H, Miremont-Salamé G, Pariente A, et al. Myocardial infarction associated with erenumab: a case report. Pharmacotherapy. 27 mai 2022
Djabarouti S, Mora P, Lahouati M, Gigan M, d’Houdain N, Sourisseau B, et al. Benefit of therapeutic drug monitoring of immunosuppressants and immunomodulators in the management of autoimmune diseases. Rev Med Interne. 25 mai 2022
Potier L, Mohammedi K, Saulnier PJ, Fumeron F, Halimi JM, Venteclef N, et al. Plasma Adrenomedullin, Allelic Variations in the ADM Gene, and Risk for Lower-Limb Amputation in People With Type 2 Diabetes. Diabetes Care. 18 mai 2022
de Courson H, Julien-Laferrière T, Georges D, Boyer P, Verchère E, Biais M. The ability of Oxygen Reserve Index® to detect hyperoxia in critically ill patients. Ann Intensive Care. 16 mai 2022
Fiore M, Sentilhes L, d’Oiron R. How I manage pregnancy in women with Glanzmann thrombasthenia. Blood. 28 avr 2022
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Sureau L, Buors C, Ianotto JC, Boyer F, Tanguy-Schmidt A, Roy L, et al. JAK2 V617F polycythemia vera and essential thrombocythemia: dynamic clinical features associated with long-term outcomes. Blood Cancer J. 8 avr 2022
Dewitte A, Defaye M, Dahmi A, Ouattara A, Joannes-Boyau O, Chermak F, et al. Prognostic Impact of Early Recovering Acute Kidney Injury Following Liver Transplantation: A Multicenter Retrospective Study. Transplantation. 1 avr 2022
Potvin J, Etchebarne I, Soubiron L, Biais M, Roullet S, Nouette-Gaulain K. Effects of capnometry monitoring during recovery in the post-anaesthesia care unit: a randomized controlled trial in adults (CAPNOSSPI). J Clin Monit Comput. avr 2022
Prével R, Dupont A, Labrouche-Colomer S, Garcia G, Dewitte A, Rauch A, et al. Plasma Markers of Neutrophil Extracellular Trap Are Linked to Survival but Not to Pulmonary Embolism in COVID-19-Related ARDS Patients. Frontiers in Immunology [Internet]. 17 mars 2022
Gerbaud E, Bouchard de La Poterie A, Baudinet T, Montaudon M, Beauvieux M-C, Lemaître A-I, et al. Glycaemic Variability and Hyperglycaemia as Prognostic Markers of Major Cardiovascular Events in Diabetic Patients Hospitalised in Cardiology Intensive Care Unit for Acute Heart Failure. J Clin Med. 11 mars 2022;
Orieux A, Prezelin-Reydit M, Prevel R, Combe C, Gruson D, Boyer A, et al. Clinical trajectories and impact of acute kidney disease after acute kidney injury in the intensive care unit: a 5-year single-center cohort study. Nephrol Dial Transplant. 3 mars 2022
Denisenko A, Ouattara A, Guinot P-G, Briant A, Fischer M-O, ICAEN group. Left ventricular unloading did not decrease mortality in cardiogenic shocks patients supported with VA-ECMO: A propensity score matching study. Anaesth Crit Care Pain Med. 17 févr 2022
Levy B, Girerd N, Amour J, Besnier E, Nesseler N, Helms J, et al. Effect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation: A Randomized Clinical Trial. JAMA. 1 févr 2022
Mohammedi K, Abouleka Y, Carpentier C, Potier L, Dubois S, Foussard N, et al. Association Between the ACE Insertion/Deletion Polymorphism and Risk of Lower-Limb Amputation in Patients With Long-Standing Type 1 Diabetes. Diabetes Care. 1 févr 2022
Orieux A, Boyer A, Dewitte A, Combe C, Rubin S. Acute kidney injury in intensive care unit: A review. Nephrol Ther. févr 2022
Fiore M, Castet S-M, Bordet J-C, Naudion S, Alessi M-C. Atypical late diagnosis of Noonan syndrome revealed by bleedings due to platelet dysfunction. J Thromb Thrombolysis. févr 2022
Martin-Latry K, Latry P, Berges C, Coste P, Douard H, Pucheu Y, et al. One-year care pathway after acute myocardial infarction in 2018: Prescription, medical care and medication adherence, using a French health insurance reimbursement database. Arch Cardiovasc Dis. févr 2022

2021

Orieux A, Boyer A, Dewitte A, Combe C, Rubin S. Acute kidney injury in intensive care unit: A review. Nephrol Ther. décembre 2021;S1769-7255(21)00508-3.
Beurton A, Ferté T, Mion S, Besnard T, Jecker O, Remy A, et al. Risk Factors of Midterm Mortality After Aortic Valve Replacement for Severe Calcified Tricuspid Aortic Valve Stenosis: A retrospective analysis of Perioperative Events Assessment in Adult Cardiac surgery (PESSAC) Registry. Journal of Cardiothoracic and Vascular Anesthesia. 1 déc 2021;35(12):3547‑56
Cavaillez T, Weinmann L, Mouton C, Delassasseigne C, Sesay M, Biais M, et al. A retrospective study of indications and consequences of monitoring direct oral anticoagulant plasma concentrations on patient care in a university hospital: The Retro-AOD study. Thromb Res. oct 2021;206:76‑83.
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Cavaillez T, Weinmann L, Mouton C, Delassasseigne C, Sesay M, Biais M, et al. A retrospective study of indications and consequences of monitoring direct oral anticoagulant plasma concentrations on patient care in a university hospital: The Retro-AOD study. Thromb Res. oct 2021;206:76‑83.
Mansour A, Decouture B, Roussel M, Lefevre C, Skreko L, Picard V, et al. Combined Platelet and Erythrocyte Salvage: Evaluation of a New Filtration-based Autotransfusion Device. Anesthesiology. 1 août 2021;135(2):246‑57.
Dumas P-Y, Villacreces A, Guitart AV, El-Habhab A, Massara L, Mansier O, et al. Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia. Clin Cancer Res. 16 août 2021;
Fiore M, Castet S-M, Bordet J-C, Naudion S, Alessi M-C. Atypical late diagnosis of Noonan syndrome revealed by bleedings due to platelet dysfunction. J Thromb Thrombolysis. 8 août 2021;
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Mercuzot C, Debien B, Riviere É, Martis N, Sanges S, Galland J, et al. Impact of a simulation-based training on the experience of the beginning of residency. Rev Med Interne. juillet 2021;S0248-8663(21)00575-0.
Orieux A, Khan P, Prevel R, Gruson D, Rubin S, Boyer A. Impact of dexamethasone use to prevent from severe COVID-19-induced acute kidney injury. Crit Care. juillet 2021;25(1):249.
Delaunay K, Sellam A, Dinet V, Moulin A, Zhao M, Gelizé E, et al. Meteorin Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration. J Clin Med. juillet 2021;10(13):2973.
Martin-Latry K, Latry P, Pucheu Y, Couffinhal T. Hospital medication adherence scale development in cardiovascular disorders. Ann Pharm Fr. juillet 2021;79(4):457‑64.
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Orieux A, Khan P, Prevel R, Gruson D, Rubin S, Boyer A. Impact of dexamethasone use to prevent from severe COVID-19-induced acute kidney injury. Crit Care. 16 juill 2021;25(1):249.
Martin-Latry K, Latry P, Pucheu Y, Couffinhal T. Validation d’une échelle de mesure de l’adhésion médicamenteuse cardiovasculaire utilisable en contexte hospitalier. Annales Pharmaceutiques Françaises. juill 2021;79(4):457‑64.
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Dewitte A, Defaye M, Dahmi A, Ouattara A, Joannes-Boyau O, Chermak F, et al. Prognostic impact of early recovering acute kidney injury following liver transplantation: a multicenter retrospective study. Transplantation. 23 juin 2021;
Perino J, Gouverneur A, Bonnet F, Lahouati M, Bernard N, Breilh D, et al. Targeting of under-75 years for the optimization of medication reconciliation with an approach based on medication risks: An observational study. Therapie. 18 juin 2021;S0040-5957(21)00151-7)
Aguerreche C, Cadier G, Beurton A, Imbault J, Leuillet S, Remy A, et al. Feasibility and postoperative opioid sparing effect of an opioid-free anaesthesia in adult cardiac surgery: a retrospective study. BMC Anesthesiol. 3 juin 2021;21(1):166.
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Rigothier C, Chauveau B, Rubin S, Combe C. Chronic kidney disease of unknown origin in agricultural communities: beyond tropical mist? Nephrol Dial Transplant. mai 2021;36(6):961‑2.
Bats M-L, Rucheton B, Fleur T, Orieux A, Chemin C, Rubin S, et al. Covichem: A biochemical severity risk score of COVID-19 upon hospital admission. PLoS One. mai 2021;16(5):e0250956.
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Bats M-L, Rucheton B, Fleur T, Orieux A, Chemin C, Rubin S, et al. Covichem: A biochemical severity risk score of COVID-19 upon hospital admission. PLoS One. 6 mai 2021;16(5):e0250956.
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Chambord J, Couzi L, Merville P, Moreau K, Xuereb F, Djabarouti S. Benefit of a pharmacist-led intervention for medication management of renal transplant patients: a controlled before-and-after study. Ther Adv Chronic Dis. 5 avr 2021;12:20406223211005276.
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Guyon J, Chapouly C, Andrique L, Bikfalvi A, Daubon T. The Normal and Brain Tumor Vasculature: Morphological and Functional Characteristics and Therapeutic Targeting. Front Physiol. 5 mars 2021;12:622615.
De Courson H, Georges D, Boyer P, Futier E, Biais M. Relationship between variations in cardiac output and end-tidal CO ₂ after phenylephrine infusion in anaesthetised patients. Br J Anaesth. 2021 Mar 2.
Tondeur S, Paul F, Riou J, Mansier O, Ranta D, Le Clech L, et al. Long-term follow-up of JAK2 exon 12 polycythemia vera: a French Intergroup of Myeloproliferative Neoplasms (FIM) study. Leukemia. mars 2021;35(3):871‑5.
Fiore M, Bayat B, Phuangtham R, Blouin L, Huguenin Y, Bein G, et al. Immunization against α _IIb β ₃ and α _v β ₃ in Glanzmann thrombasthenia patients carrying the French Gypsy mutation. J Thromb Haemost. 2021 Jan 10;19(1):255–61.
Bertrand C, Saulnier P-J, Potier L, Croyal M, Blanchard V, Gand E, et al. Plasma concentrations of lipoproteins and risk of lower-limb peripheral artery disease in people with type 2 diabetes: the SURDIAGENE study. Diabetologia.2021 Jan 6;
Mohammedi K, Harrap S, Mancia G, Marre M, Poulter N, Chalmers J, et al. History of lower-limb complications and risk of cancer death in people with type 2 diabetes. Cardiovasc Diabetol. 2021 Jan 4;20(1):3.
Hernández-Ruiz V, Forestier E, Gavazzi G, Ferry T, Grégoire N, Breilh D, et al. Subcutaneous Antibiotic Therapy: The Why, How, Which Drugs and When. Journal of the American Medical Directors Association. 2021 Jan;22(1):50-55.e6.
Rigalleau V, Foussard N, Bertrand A, Monlun M, Blanco L, Mohammedi K. Lung cancer and diabetes: A role for advanced glycation end-products? Eur J Clin Invest. 2021 Jan;51(1):e13389.

2020

Tauzin-Fin P, Barrucand K, Sesay M, Roullet S, Gosse P, Bernhard J-C, Robert G, Sztark F. Peri-operative management of pheochromocytoma with intravenous urapidil to prevent hemodynamic instability: A 17-year experience. J Anaesthesiol Clin Pharmacol 2020;36:49.
Rozé H, Repusseau B, Perrier V, Zaouter C, Ouattara A. Regional referral ECMO centre decision and mid-term mortality of patients suffering severe Acute Respiratory Distress Syndrome (ARDS). Anaesth Crit Care Pain Med. déc 2020;39(6):886‑7.
Mion S, Duval B, Besnard T, Darné B, Mouton C, Jecker O, et al. U-shaped relationship between pre-operative plasma fibrinogen levels and severe peri-operative bleeding in cardiac surgery. Eur J Anaesthesiol. oct 2020;37(10):889‑97.
Bonello L, Delmas C, Gaubert M, Schurtz G, Ouattara A, Roubille F. Trials of mechanical circulatory support with percutaneous axial flow pumps in cardiogenic shock complicating acute myocardial infarction: Mission impossible? Arch Cardiovasc Dis. juill 2020;113(6‑7):448‑60
Mauriat P, Bojan M, Soulie S, Foulgoc H, Tafer N, Ouattara A. Impact of the perioperative inotropic support in grown-up congenital heart patients undergoing cardiac surgery: a propensity score adjusted analysis. Ann Intensive Care. 9 juill 2020;10(1):91.
Rubin S, Orieux A, Prevel R, Garric A, Bats M-L, Dabernat S, Camou F, Guisset O, Issa N, Mourissoux G, Dewitte A, Joannes-Boyau O, Fleureau C, Rozé H, Carrié C, Petit L, Clouzeau B, Sazio C, Bui H-N, Pillet O, Rigothier C, Vargas F, Combe C, Gruson D, Boyer A. Characterization of acute kidney injury in critically ill patients with severe coronavirus disease 2019. Clinical Kidney Journal 2020;sfaa099.
Paugam-Burtz C, Levesque E, Louvet A, Thabut D, Amathieu R, Bureau C, Camus C, Chanques G, Faure S, Ferrandière M, Francoz C, Galbois A, Gustot T, Ichai C, Ichai P, Jaber S, Lescot T, Moreau R, Roullet S, Saliba F, Thévenot T, Velly L, Weiss E. Management of liver failure in general intensive care unit. Anaesth Crit Care Pain Med 2020;39:143–161.
Lapoirie J, Contis A, Guy A, Lifermann F, Viallard J-F, Sentilhes L, James C, Duffau P. Management and outcomes of 27 pregnancies in women with myeloproliferative neoplasms. J Matern Fetal Neonatal Med 2020;33:49–56.
Gruel Y, De Maistre E, Pouplard C, Mullier F, Susen S, Roullet S, Blais N, Le Gal G, Vincentelli A, Lasne D, Lecompte T, Albaladejo P, Godier A, Albaladejo P, Belisle S, Blais N, Bonhomme F, Borel-Derlon A, Borg JY, Bosson J-L, Cohen A, Collet J-P, Maistre E de, Faraoni D, Fontana P, Huet DG, Godier A, Gruel Y, Guay J, Hardy JF, et al. Diagnosis and management of heparin-induced thrombocytopenia. Anaesth Crit Care Pain Med 2020;39:291–310.
Boutin J, Bats M-L, Amintas S, Bérard A, Dabernat S, Colombies B, Rucheton B, Bedel A. Pigments test strips: A rapid companion test to exclude sub-arachnoid haemorrhage. Clin Chim Acta 2020;54–59.

2019

Vial G, Rivière E, Raymond A-A, James C, Di-Tommaso S, Dugot-Senant N, Dupuy J-W, Yacoub M, Parrens M, Saltel F, Viallard J-F. Antigenic Mimicry in Paraneoplastic Immune Thrombocytopenia. Front Immunol 2019;10:523.
Mansier O, Prouzet-Mauléon V, Jégou G, Barroso K, Raymundo DP, Chauveau A, Dumas P-Y, Lagarde V, Turcq B, Pasquet J-M, Viallard J-F, James C, Praloran V, Voutetakis K, Chatziioannou A, Mahon F-X, Chevet E, Lippert E. The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation. Cancers (Basel) 2019;11.
Zaouter C, Oses P, Assatourian S, Labrousse L, Rémy A, Ouattara A. Reduced Length of Hospital Stay for Cardiac Surgery—Implementing an Optimized Perioperative Pathway: Prospective Evaluation of an Enhanced Recovery After Surgery Program Designed for Mini-Invasive Aortic Valve Replacement. Journal of Cardiothoracic and Vascular Anesthesia 2019;33:3010–3019.
Susen S, Gruel Y, Godier A, Harroche A, Chambost H, Lasne D, Rauch A, Roullet S, Fontana P, Goudemand J, Maistre E de, Chamouard V, Wibaut B, Albaladejo P, Négrier C. Management of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra ^® ): Proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in collaboration with the French Working Group on Perioperative Haemostasis (GIHP). Haemophilia 2019;25:731–737.
Roullet S, Maistre E de, Ickx B, Blais N, Susen S, Faraoni D, Garrigue D, Bonhomme F, Godier A, Lasne D. Position of the French Working Group on Perioperative Haemostasis (GIHP) on viscoelastic tests: What role for which indication in bleeding situations? Anaesth Crit Care Pain Med 2019;38:539–548.
Roullet S, Weinmann L, Labrouche S, Gisbert-Mora C, Biais M, Revel P, Freyburger G. Fibrinolysis in trauma patients: wide variability demonstrated by the Lysis Timer. Scand J Clin Lab Invest 2019;79:136–142.
Roullet S, Labrouche S, Mouton C, Quinart A, Nouette-Gaulain K, Laurent C, Freyburger G. Lysis Timer: a new sensitive tool to diagnose hyperfibrinolysis in liver transplantation. J Clin Pathol 2019;72:58–65.
Roullet S, Labrouche S, Freyburger G. Fibrinolysis during liver transplantation: analysis by the Thrombodynamics method. J Clin Pathol 2019;72:636–638.
Roullet S, Labrouche S, Freyburger G. Comparison of Two Thrombin Generation Methods, CAT and ST-Genesia, in Liver Transplant Patients. Thromb Haemost 2019;119:899–905.
Roullet S, Labrouche S, Chiche L, Nouette-Gaulain K, Laurent C, Freyburger G. The Thrombodynamics® analyzer: A new thrombin generation analyzer compared to the Calibrated Automated Thrombogram® in liver transplantation. Thromb Res 2019;175:37–39.
Rivière E, Schwartz P, Machelart I, Greib C, Pellegrin J-L, Viallard J-F, Lazaro E. Neurosarcoidosis and infliximab therapy monitored by 18FDG PET/CT. QJM: An International Journal of Medicine 2019;112:695–697.
Poullenot F, Ollivier J, Rivière P, Sauvaget L, Berroneau A, Djabarouti S, Xuereb F, Zerbib F, Breilh D, Laharie D. Implementation of infliximab standardized doses after pharmacokinetic modelization in a cohort of patients with Crohn’s disease. Dig Liver Dis 2019;52:408–413.
Ollivier J, Carrié C, Houdain N d’, Djabarouti S, Petit L, Xuereb F, Legeron R, Biais M, Breilh D. Are Standard Dosing Regimens of Ceftriaxone Adapted for Critically Ill Patients with Augmented Creatinine Clearance? Antimicrob Agents Chemother 2019;63:e02134-18.
Luque Paz D, Mansier O, Riou J, Conejero C, Roy L, Belkhodja C, Ugo V, Giraudier S. Positive impact of molecular analysis on prognostic scores in essential thrombocythemia: a single center prospective cohort experience. Haematologica 2019;104:e134–e137.
Gerbaud E, Darier R, Montaudon M, Beauvieux M-C, Coffin-Boutreux C, Coste P, Douard H, Ouattara A, Catargi B. Glycemic Variability Is a Powerful Independent Predictive Factor of Midterm Major Adverse Cardiac Events in Patients With Diabetes With Acute Coronary Syndrome. Diabetes Care 2019;42:674–681.
Garandeau D, Noujarède J, Leclerc J, Imbert C, Garcia V, Bats M-L, Rambow F, Gilhodes J, Filleron T, Meyer N, Brayer S, Arcucci S, Tartare-Deckert S, Ségui B, Marine J-C, Levade T, Bertolotto C, Andrieu-Abadie N. Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas. Mol Cancer Ther 2019;18:289–300.
Forcade E, Bonnin A, Desoutter J, Nacimento F, Roch-Torreilles I, Vigneron F, Boiron J-M, Yakoub-Agha I, Simon N. Clinical pharmacy in a bone marrow and cellular therapy transplantation ward-which methods to put in place: Guidelines from the francophone Society of bone marrow transplantation and cellular therapy (SFGM-TC). Bull Cancer 2019;106:S59–S70.
Durand P, Furudoi A, Parrens M, Lazaro E, Viallard J, Rivière E. Complete remission of immune thrombocytopenia in a 30‐year old woman after excision of a right atrial myxoma. Br J Haematol 2019;16135.
Dumas P-Y, Naudin C, Martin-Lannerée S, Izac B, Casetti L, Mansier O, Rousseau B, Artus A, Dufossée M, Giese A, Dubus P, Pigneux A, Praloran V, Bidet A, Villacreces A, Guitart A, Milpied N, Kosmider O, Vigon I, Desplat V, Dusanter-Fourt I, Pasquet J-M. STAT5-and hypoxia-dependent upregulation of AXL. Haematologica 2019;104:2017–2027.
Courson H de, Michard F, Chavignier C, Verchère E, Nouette-Gaulain K, Biais M. Do changes in perfusion index reflect changes in stroke volume during preload-modifying manoeuvres? J Clin Monit Comput 2019;
Courson H de, Ferrer L, Cane G, Verchère E, Sesay M, Nouette-Gaulain K, Biais M. Evaluation of least significant changes of pulse contour analysis-derived parameters. Ann Intensive Care 2019;9:116.
Courson H de, Boyer P, Grobost R, Lanchon R, Sesay M, Nouette-Gaulain K, Futier E, Biais M. Changes in dynamic arterial elastance induced by volume expansion and vasopressor in the operating room: a prospective bicentre study. Ann Intensive Care 2019;9:117.
Bret V-E, Pougault B, Guy A, Castet S, Huguenin Y, Pillois X, James C, Fiore M. Assessment of light transmission aggregometry on the routine coagulation analyzer Sysmex CS-2500 using CE-marked agonists from Hyphen Biomed. Platelets 2019;30:540–542.
Breilh D, Honore PM, De Bels D, Roberts JA, Gordien JB, Fleureau C, Dewitte A, Coquin J, Rozé H, Perez P, Attou R, Redant S, Kugener L, Saux M-C, Spapen HD, Ouattara A, Joannes-Boyau O, __. Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: Lessons learned from an ancillary study of the IVOIRE trial. Journal of Translational Internal Medicine 2019;7:155–169.

2018

Zaouter C, Priem F, Leroux L, Bonnet G, Bats M-L, Beauvieux M-C, Rémy A, Ouattara A. New markers for early detection of acute kidney injury after transcatheter aortic valve implantation. Anaesth Crit Care Pain Med 2018;37:319–326.
Zaouter C, Potvin J, Bats M-L, Beauvieux M-C, Remy A, Ouattara A. A combined approach for the early recognition of acute kidney injury after adult cardiac surgery. Anaesth Crit Care Pain Med 2018;37:335–341.
Roullet S, Labrouche S, Carrie C, Auque H, Berard X, Freyburger G. Multiplate® evaluation of acetylsalicylic acid efficacy in carotid surgery: routine and genetic influencing factors. J Thromb Haemost 2018;16:583–591.
Georges D, De Courson H, Lanchon R, Sesay M, Nouette-Gaulain K, Biais M. End-expiratory occlusion maneuver to predict fluid responsiveness in the intensive care unit : an echocardiographic study. Crit Care 2018;22:32.
Furudoï A, Rivière É, Lazaro E, Furudoï E, Viallard J-F, Parrens M. Adult Primary Immune Thrombocytopenia: Spleen Histology Findings and Outcomes According to Rituximab Use Based on Analysis of 41 Cases. Am J Surg Pathol 2018;42:401–412.
Dewitte A, Lepreux S, Villeneuve J, Rigothier C, Combe C, Ouattara A, Ripoche J. Correction to : Blood platelets and sepsis pathophysiology : A new therapeutic prospect in critically ill patients ? Ann Intensive Care 2018;8:32.
Dallaudiere B, Crombé A, Gadeau AP, Pesquer L, Peuchant A, James C, Silvestre A. Iodine contrast agents do not influence Platelet-Rich Plasma function at an early time point in vitro. J Exp Orthop 2018;5:47.
Carrié C, Legeron R, Petit L, Ollivier J, Cottenceau V, Houdain N d’, Boyer P, Lafitte M, Xuereb F, Sztark F, Breilh D, Biais M. Higher than standard dosing regimen are needed to achieve optimal antibiotic exposure in critically ill patients with augmented renal clearance receiving piperacillin-tazobactam administered by continuous infusion. J Crit Care 2018;48:66–71.

2017

Zaouter C, Hemmerling TM, Mion S, Leroux L, Remy A, Ouattara A. Feasibility of Automated Propofol Sedation for Transcatheter Aortic Valve Implantation: A Pilot Study. Anesth Analg 2017;125:1505–1512.
Royston D, De Hert S, Van Der Linden J, Ouattara A, Zacharowski K. A special article following the relicence of aprotinin injection in Europe. Anaesth Crit Care Pain Med 2017;2.
Pintat J, Silvestre A, Magalon G, Gadeau AP, Pesquer L, Perozziello A, Peuchant A, Mounayer C, Dallaudière B. Intra-articular Injection of Mesenchymal Stem Cells and Platelet-Rich Plasma to Treat Patellofemoral Osteoarthritis: Preliminary Results of a Long-Term Pilot Study. J Vasc Interv Radiol 2017;28:1708–1713.
Legeron R, Xuereb F, Chaignepain S, Gadeau A-P, Claverol S, Dupuy J-W, Djabarouti S, Couffinhal T, Schmitter J-M, Breilh D. A new reliable, transposable and cost-effective assay for absolute quantification of total plasmatic bevacizumab by LC–MS/MS in human plasma comparing two internal standard calibration approaches. J Chromatogr B Analyt Technol Biomed Life Sci 2017;1070:43–53.
Lanchon R, Nouette-Gaulain K, Stecken L, Sesay M, Lefrant JY, Biais M. Dynamic Arterial Elastance Obtained Using Arterial Signal Does Not Predict An Increase In Arterial Pressure After A Volume Expansion in the Operating Room. Anaesth Crit Care Pain Med 2017;36:377–382.
Jung B, Mahul M, Breilh D, Legeron R, Signe J, Jean-Pierre H, Uhlemann AC, Molinari N, Jaber S. Repeated Piperacillin-Tazobactam Plasma Concentration Measurements in Severely Obese Versus Nonobese Critically Ill Septic Patients and The Risk of Under and Overdosing. Crit Care Med 2017;45:e-470-e478.
Dewitte A, Lepreux S, Villeneuve J, Rigothier C, Combe C, Ouattara A, Ripoche H. Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients? Ann Intensive Care 2017;7(1):115.
Courteille B, Brunet J, Ouattara A, Stéphan F, Gérard JL, Lorne E, Fischer MO, Arcothova. Protective ventilation during cardiac surgery: More than tidal volume? Anaesth Crit Care Pain Med 2017;36:133–134.
Chauveau A, Nibourel O, Tondeur S, Paz DL, Mansier O, Paul F, Wemeau M, Preudhomme C, Lippert E, Ugo V. Absence of CALR mutations in JAK2-negative polycythemia. Haematologica 2017;102:e15–e16.
Biais M, Stecken L, Martin A, Roullet S, Quinart A, Sztark F. Automated, continuous and non-invasive assessment of pulse pressure variations using CNAP® system. J Clin Monit Comput 2017;31:685–692.
Biais M, Mazocky E, Stecken L, Pereira B, Sesay M, Roullet S, Quinart A, Sztark F. Impact of Systemic Vascular Resistance on the Accuracy of the Pulsioflex Device. Anesth Analg 2017;124:487–493.
Biais M, Lanchon R, Sesay M, Le Gall L, Pereira B, Futier E, Nouette-Gaulain K. Changes in Stroke Volume Induced by Lung Recruitment Maneuver Predict Fluid Responsiveness in Mechanically Ventilated Patients in the Operating Room. Anesthesiology 2017;126(2):260–267.
Biais M, De Courson H, Lanchon R, Pereira B, Bardonneau G, Griton M, Sesay M, Nouette-Gaulain K. Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room. Anesthesiology 2017;127:450–456.
Aussel A, Thébaud NB, Bérard X, Brizzi V, Delmond S, Bareille R, Siadous R, James C, Ripoche J, Durand M, Montembault A, Burdin B, Letourneur D, L’Heureux N, David L, Bordenave L. Chitosan-based hydrogels for developing a small-diameter vascular graft: in vitro and in vivo Biomed Mater 2017;12:065003.

2016

Zaouter C, Cornolle C, Labrousse L, Ouattara A. Perioperative management of a patient undergoing a novel mini-invasive percutaneous transcatheter left ventricular reconstruction procedure. J Clin Anesth 2016;203–207.
Selle F, James C, Tuffigo M, Pillois X, Viallard J-F, Alessi M-C, Fiore M. Clinical and Laboratory Findings in Patients with δ-Storage Pool Disease: A Case Series. Semin Thromb Hemost 2016;43:048–058.
Roze H, Doassans-Cazaban G, Repusseau B, Ouattara A. Decrease of thoracopulmonary compliance with pressure assist controlled ventilation in ARDS patients under ECMO and transported to a referral centre. Intensive Care Med 2016;43(1):148–149.
Mansier O, Migeon M, Etienne G, Bidet A, Lippert E. JAK2V617F and CALR double mutations are more frequently encountered in patients with low JAK2V617F allelic burdens. Leukemia & Lymphoma 2016;57:1949–1951.
Freynet A, Gobaille G, Joanes-Boyau O, Grandet P, Fleureau C, Ripoche J, Dewitte A, Ouattara A. Effects of chest physiotherapy by expiratory flow increase on secretion removal and lung mechanics in ventilated patients: a randomized crossover study. Intensive Care Med 2016;1090–1091.
Dewitte A, Carles P, Joannes-Boyau O, Fleureau C, Roze H, Combe C, Ouattara A. Bioelectrical impedance spectroscopy to estimate fluid balance in critically ill patients. J Clin Monit Comput 2016;227–233.